Y4 Pharma Flashcards

(41 cards)

1
Q

Methotrexate

A

DMARD

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2
Q

Hydroxychloroquine

A

DMARD

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3
Q

Sulphasalazine

A

DMARD

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4
Q

Leflunomide

A

DMARD

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5
Q

Mirtazapine

A

Anti-depressant which also helps with insomnia

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6
Q

Certolizumab
Etanercept
Adalimumab
Infliximab
Golimumab

A

Biologics which target inflamatory cytokine TNF

Mab - maybe you qualify for biologics

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7
Q

Abatacept

A

Biologic which inhibits T-cell response

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8
Q

Rituximab
Belimumab

A

Biologics that inhibit b-cells

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9
Q

Upadacitinib
Baricitinib
Tofacitinib

A

Biologics which are Janus Kinase (JAK) inhibitors

Janus Kinase (JAK) is a mediator of cytokine signals

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10
Q

Tocilizumab
Sarilumab

A

Biologics which target inflamatory cytokine IL-6

Mab - maybe you qualify for biologics

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11
Q

Secukinumab
Ixekizumab

A

Biologics which target inflamatory cytokine IL-17

Mab - maybe you qualify for biologics

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12
Q

Ustekinemab
Guselkumab

A

Biologics which target inflamatory cytokine IL-12/23

Mab - maybe you qualify for biologics

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13
Q

Lithium

A

Used to treat bipolar

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14
Q

Ceftriazone

A

First line antibiotic for bacterial meningitis

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15
Q

Methenamine Hippurate

A

Used to decrease the frequency of reccurent UTIs.

Converts to formaldahyde in the acidic environment of the bladder.

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16
Q

Alendronate

A

Bisphosphonate

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17
Q

Denosumab

A

Antibody that blocks RANKL and hence used to treat osteoporosis

18
Q

Romosozumab

A

Antibody which encourages osteoblast activity by blocking the action of sclerostin (osteoblast inhibiter).

Used to treat severe osteoporosis.

19
Q

Colchicine

A

Used for 6months in initial treatment of gout to prevent acute flares alongside allopurinol long term treatment

20
Q

leukotriene receptor antagonist (LTRA)

A

An inhaler used as a 3rd/4th asthma treatment.

Can’t be used for COPD

21
Q

Formoterol

A

LABA used in ART and MART. It is better that salmeterol because it is faster acting so can used as a releiver

22
Q

Nintedanib

A

Used in treatment of idiopathic pulmonary fibrosis

23
Q

Pirfenidone

A

Anti-fibvrotic used in treatment of idiopathic pulmonary fibrosis

24
Q

Rifampin, Isoniazid, Pyrazinamide, and Ethambutol.

A

RIPE

The four TB meds.

Give all four for two months then continue RI for another 4 months.

25
Terlipressin
Vasopressin analogue Splanchic vasoconstrictor Used in bleeding oesophageal varices
26
Mesalazine
Used ot treat UC and crohn's and bring into remission
27
Rifaximin
Used to treat diarrhoea caused by e-coli and prevents hepatic encephalopathy
28
Lactalose
Laxative
29
Tacrolimus
Immunosuppressant commonly used in organ transplants
30
Budesonide
Steroid with high first past metabolism. This makes it good for treating the gut without having too many systemic side effects.
31
Macrogol Brand name?
Laxitive Works by creating an osmotic gradient drawing water into the bowel. Brand name is movicol
32
Azathioprine
Immunosuppressant effective against IBD.
33
Erythromycin low dose
High dose - antibiotic Low dose - Pro kinetic
34
Budesonide
Steroids are useful for GI-related inflammation such as microscopic colitis and eosinophilic oesophagitis. It has a high first pass metabolism, therefore doesn't enter the bloodstream and cause as many systemic side effects.
35
Digoxin
Second-line treatment after beta blockers for heart failure and AF
36
Dalbavancin
If the infection is sensitive to this it can be a useful antimicrobial in patients with a chaotic lifestyle, as it has a long half-life so doses can be a once weekly dose
37
Cholestyramine
Bile-binding medication used in bile malabsorption
38
Cabergoline
Dopamine agonist used to treat hyperprolactinaemia
39
Duloxetine
SSRI Also used to treat musculoskeletal pain, fibromyalgia and health anxiety.
40
Inclisiran
Inclisiran is a first-in-class small interfering RNA (siRNA) therapy that lowers LDL cholesterol. It is given 6monthly so good for people with chaotic lifestyles.
41