05 - Leishmania

Question 1

(Leishmania)

1. What form in vertebrates?
2. live where?

Answer 1

1. amastigote
2. inside macrophages, within phagolysosoms

Question 2

(Leishmania)

(Hosts)

1. are what?
2. vectors?

Answer 2

1. vertebrates (mammals primarily)
2. sand flies

Question 3

Question 4

Answer 4

Question 5

(L. Infantum)

1. Had only been observed where?
2. Zoonotic viesceral leishmaniasis

what are the natural reservoir host?

(Canine visceral leishmaniasis)

3. dogs also get sick
4. involvement of what?

Answer 5

1. the old world (Asia, Middle east, southern europe, NW Africa
2. dogs
3. visceral and cutaneous involvement

Question 6

Answer 6

Question 7

Question 8

L. Infantum

Transmission

1. has to fit foxhound only pattern
2. what is transmission?

Answer 8

2. direct dog-to-dog transmission

biting, reusing needles for injections, blood transfusions, breeding (transplacental transmission)

Question 9

L. Infantum

Transmission

(Sandflies)

1. Some N American Sandfy species have become infected after doing what?

(But are they competent vectors?)

2. well?

Answer 9

1. feeding on L. infantum-infected dogs
2. if canine reservoir becomes larger and more dispersed, the possibility of vector-borne transmission will increase (zoonotic risk)

Question 10

(L. infantum in foxhounds)

1. What kind of infection?

Answer 10

1. autochthonous infection