1. Intro Flashcards

(43 cards)

1
Q

microscopic pathology fields

A
  • haematology
  • immunology
  • microbiology
  • virology
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2
Q

developmental pathology

A
  • teratology
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3
Q

pathogenesis

A

mechanism of development

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4
Q

gross pathology tools

A

autopsy

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5
Q

microscopic pathology tools

A

histology

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6
Q

molecular pathology tools

A
  • cell isolation and culture
  • HIC
  • FISH
  • lab molecular biology
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7
Q

caudal

A

tail end

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8
Q

rostral

A

nose end

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9
Q

supine

A

laying on back/ upwards facing

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10
Q

prone

A

laying on stomach/ downwards facing

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11
Q

palmar

A

hand end

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12
Q

plantar

A

foot end

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13
Q

Haematoxylin and Eosin stains

A

H - stains nucleic acids blue
E - stains elastin and collagen pink

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14
Q

epithelia protective functions

A
  • against mechanical damage
  • against fluid loss
  • against foreign body invasion
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15
Q

epithelial metabolic functions

A
  • ion transport/ metabolite exchange
  • glandular secretion
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16
Q

Cardiac muscle features

A
  • coordination of contraction (intercalated discs)
  • striated
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17
Q

smooth muscle feature

A
  • spindle shaped
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18
Q

adipose histology

A
  • loose, designed to hold lipids
19
Q

bone histology

A
  • highly organised for strength and rigidity
20
Q

tendon histology

A
  • elongated fibres to transmit force
  • flattened cells to withstand pressure
21
Q

erythrocyte key features (giemsa stain)

A
  • pink-red biconcave disc
  • anucleate
22
Q

monocyte key features (giemsa stain)

A
  • large
  • mononuclear
  • kidney-shaped nucleus
23
Q

lymphocyte key features (giemsa stain)

A
  • mononuclear
  • variable size and shape
24
Q

neutrophil key features (giemsa stain)

A
  • segmented nucleus with 2-5 lobes
  • small pink-purple granules
25
Eosinophils key features (giemsa stain)
- 2-3 lobes - large orange-red granules
26
Basophil key features (giemsa stain)
- 2 lobes - large dark blue-purple granules - obscure nucleus
27
Platelet key features (giemsa stain)
- small pale purple-blue cytoplasmic fragments - small purple granules
28
Erythrocyte function
Transports O2 and CO2 via Hb
29
Monocyte function
Phagocytosis (after transforming in to macrophage)
30
Lymphocyte function
mediates immune response (B, T, and NK cells)
31
neutrophil function
phagocytosis
32
Eosinophil function
- allergic reactions - defence against parasites
33
Basophil function
- Binds IgE - releases histamine to intensify inflammatory response
34
Platelet function
- blood clotting
35
GI layers
- mucosa - submucosa - muscularis (propria) - adventitia
36
GI mucosa layers
- epithelium - laminated propria - muscularis mucosa
37
Blood vessel layers
- tunica intima - tunica media - tunica adventitia
38
tunica intima
endothelium and supporting tissue
39
tunica media
- smooth muscle for contraction
40
tunica adventitia
collagen for attachment and strength
41
size of tunica media significance
reflects blood pressure - artery - thicker - veins - thinner
42
The pillars of pathology
- cause - pathogenesis - structural alteration of cells - the consequences of changes in
43
pathological significance of epithelia
- majority of cells - exposed to external environment and pathogens