2/16

Question 1

Clomiphene

Answer 1

• Hypothalamus estrogen receptor blocker. Prevents negative feedback estrogen has on GnRH.
• this inc. FSH & LH production which stimulates ovulation.
• used to treat infertility due to anovulation.
• can cause visual disturbances.

Question 2

Danazol

Answer 2

-partial androgen agonist
-used for endometriosis & hereditary angioedema.
-

Question 3

Ticlopidine

Answer 3

• ADP receptor inhibitors
• this inhibits Gp2b/3a from being placed on receptor surface.
• watch out for neutropenia! (can present as mouth ulcers).

Question 4

Argatroban, bivalirudin

Answer 4

• derivatives of hirudin - the anticoagulant used by leeches.
• directly inhibit thrombin.
• used instead of heparin for pts w/HIT (heparin induced thrombocytopenia).

Question 5

Abciximab side effects

Answer 5

thrombocytopenia

Question 6

what causes 99% of mitral stenosis

Answer 6

rheumatic heart disease

Question 7

cladribine

Answer 7

• adenosine analog
• inhibits adenosine deaminase (adenosine buildup is toxic - like in SCID)
• treatment for hairy cell leukemia.

Question 8

Modafinil

Answer 8

• 1st line treatment for modafinil.
• non-amphetamine stimulant.
• P450 inducer

Question 9

De Quervain’s thyroiditis

Answer 9

• granulomas
• jaw pain, tender thyroid
• assoc. w/mumps & coxsackie
• potential early thyrotoxicosis.

Question 10

vemurafenib

Answer 10

• BRAF (V600E mutation specific) kinase inhibitor

- used for metastatic melanoma

Question 11

Whipple disease

Answer 11

• FOAMy WHIPPed cream in a CAN
• PAS (+) foamy macrophages in lamina propria
• Cardiac Sxs
• Arthralgias
• Neuro Sxs

Question 12

pudendal nerve block

-landmark?

Answer 12

• ischial spine.
• relieve pain of delivery
• S2-S4

Question 13

Scaphoid. Whats unique about its blood supply?

Answer 13

Retrograde blood supply.

-avascular necrosis common here.

Question 14

Dislocation of which bone can cause acute carpal tunnel?

Answer 14

lunate

Question 15

Guyon canal syndrome. Which nerve compressed?

Answer 15

ulnar nerve.

-commonly seen in cyclists due to pressure from handlebars.

Question 16

Long thoracic nerve

• which nerves and where does it originate from?
• damage causes what?

Answer 16

roots of C5 - C7.

-winged scapula

Question 17

Mnemonic for terminal branches of brachial plexus

Answer 17

my aunty raped my uncle

• musculocutaneous
• axillary
• radial
• median
• ulnar

Question 18

Axillary n.

Answer 18

C5-C6

Question 19

musculocutaenous n.

Answer 19

C5-C7

Question 20

radial n.

Answer 20

C5-T1

Question 21

median n.

Answer 21

C5-T1

Question 22

ulnar n.

Answer 22

C8-T1

Question 23

Recurrent branch of median n.

Answer 23

C5-T1