What is nutrition?
The process of securing the dietary requirements of an individual or of a population
What are macronutrients and micronutrients?
Macronutrients - required in comparatively large amounts e.g. fat, carbohydrate, protein, water
Micronutrients - required in small amounts e.g. minerals and vitamins
What are different ways of gathering nutritional surveillance data?
Wants some more general points + UK specific examples
Food supply data
- Food production and imports/exports (conducted by UN)
- Ad hoc food mapping may also be done e.g. to identify food deserts
Food expenditure surveys
- E.g. ONS Living Costs and Food Survey
Diet and nutrition surveys
- Food diaries can be biased as overweight people more likely to underestimate food intake
Nutritional surveillance in children
- Breastfeeding: Infant feeding survey
- Proportion of children eating school meals
- National Child Measurement Programme
Study designs to assess nutrition
- Ecological (potential for confounding and ecological fallacy)
- Case-control (recall bias)
- Cohort
- RCTs (very expensive, effect sizes tend to be small for diet so may need meta-analysis)
Short term nutritional problems
Sugar –> dental caries
Low salt –> hypotension
Low protein –> Kwashiorkor (muscle wasting, protruding abdomen, fatigue, diarrhoea)
Low protein and calories –> marasmus (emaciation)
Low Vit C –> Scurvy (gum disease, bleeding, listlessness)
Low Vit B1 –> Beriberi (heart failure, generalised oedema, neuropathy)
Low Vit D in children –> Osteomalacia and rickets
Low Vit D in adults –> Osteoporosis
Low folate –> Anaemia, neural tube defects
Iron deficiency –> Anaemia
Long term nutritional problems
Central obesity –> T2DM
Low fruit and veg –> CHD and some cancers
Low Ca –> osteoporosis
What is malnutrition?
A lack or excess of any component of the diet
What are the impacts of malnutrition in pregnancy?
Leads to IUGR which is associated with stillbirth, CLD, hypoxic brain injury. Can also lead to long-term impacts e.g. CVD, renal disease, impaired cognitive development.
What are the impacts of malnutrition on disease aetiology?
NB Disease can also cause malnutrition: illness –> reduced appetite –> worsened malnutrition
What are the impacts of malnutrition on growth and development
Acute malnutrition can lead to children being underweight and to wasting
Chronic malnutrition can also lead to underweight and to stunting
What are the different markers of nutritional status?
Anthropometry
- BMI
- Growth charts (height and weight)
- Head circumference in infants
- Skinfold thickness
Indices of malnutrition
- Malnutrition Universal Screening Tool (MUST)
Biochemical tests
- Plasma fatty acids
- Urinary sodium
- Urinary nitrogen (marker of protein)
Bioelectrical impedance
- Measuring body composition
Imaging
- Infrared or X-rays for body fat percentage
Food consumption surveys
- Ask about food intake
- Duplicate diet method: people weigh out two portions of their meal and one is sent to chemical analysis
What are examples of nutritional interventions?
How can you measure the impact of nutritional interventions?
What are the different determinants of dietary choices?
Social determinants
- Poverty
- Culture
- Education
Behavioural determinants
- Attitudes and beliefs
- Psychological e.g. mood and stress
What are different dietary reference values (DRVs)
Estimated average requirement (EAR): Average amount needed by a group (i.e. 50% of people’s requirements are met)
Reference nutrient intake (RNI): Amount that meets needs of 97.5% of the group (meets need of vast majority)
Lower reference nutrient intake (LRNI): Amount that meets needs of 2.5% (most will need more)
Safe intake: Issued when insufficient evidence for EAR, RNI and LRNI
What is the evidence for nutritional recommendations?
Some evidence is ecological e.g.
- Intersalt demonstrated salt linked to BP
- Seven Countries demonstrated links between heart disease and dietary fat
Health effects of recreational drugs
What are different types of diets and their health effects?
Western diet
- High total energy –> obesity
- High saturated fats (butter, red meat) –> obesity, CVD, cancers
- Low fibre –> Colorectal cancer
- High salt –> CVD
Mediterranean diet
- High unsaturated fats (olive oil) –> low cholesterol and CVD risk
- High fruit and veg and less red meat –> lower cancer risk and obesity
South Asian diet
- High saturated fats –> Obesity, CVD
- High fruit and veg
? - High carb –> T2DM (this is just my idea)
What are the different approaches that can be applied to complex issue such as diet, alcohol, smoking etc?
Medical approach
- Prevention is focussed on risk factors and pharmacological interventions
Socioenvironmental approach
- Recognised the role of structural factors e.g. social, political and economic environment
- A: evidence of effectiveness e.g. legislation on salt in food; may help to reduce inequalities
- D: “nanny state” critique by libertarians
Behavioural approach
- Focussed on individual choice and education
- May use social marketing approaches
- Limitations: ignores structural, social and cultural factors
Advantages and disadvantages of “Nudge” theory
Adv:
- Does not restrict individual choice
- Low cost
- Simple and rapid
- Some evidence of effectiveness
Disadvantages:
- Ill-defined
- Little large scale evidence
- Arguably less effective than legislation
- May widen inequalities