What are the axes on a flow-volume loop?
Y-axis = flow (L/s); X-axis = volume (L)
Flow vs volume shows both inspiration and expiration patterns.
What does PEF represent on a flow-volume loop?
Peak Expiratory Flow – the highest flow reached during a forced exhalation
Shows how quickly air leaves the lungs at the start of the maneuver.
Define FEF 25%, FEF 50%, and FEF 75%.
They reflect flow in the mid-to-small airways and indicate airway resistance.
What does FVC stand for and what does it represent on an FVL?
Forced Vital Capacity – the total volume exhaled forcefully after full inspiration
It’s the width of the loop along the X-axis.
Why can’t FEV₁ be precisely placed on a flow-volume loop?
Because FEV₁ is a time-based value (volume exhaled in 1 second)
The loop shows flow vs volume, not time.
How do you identify inspiration and expiration on an FVL?
The upper (positive) curve = expiration; the lower (negative) curve = inspiration
This distinction helps in analyzing lung function.
What shape indicates normal expiratory flow on an FVL?
A sharp rise to PEF followed by a linear or slightly concave decline
Smooth = healthy; “scooped-out” = obstructive.
Fill-in-the-blank: “Peak up, _____ slows down.” → What concept does this describe?
Flow slows down
As the lungs empty, flow decreases due to less recoil and higher airway resistance.
What are the axes on a volume-time graph?
Y-axis = volume (L); X-axis = time (seconds)
This graph is essential for assessing lung function over time.
What does the steep initial rise on the expiration curve indicate?
Rapid early exhalation → good patient effort and high PEF
Indicates effective lung function.
What does FEV₁ represent on this graph?
The volume exhaled in the first second of a forced exhalation
Key for detecting obstruction.
What does the plateau on the volume-time graph indicate?
The point where no more air can be exhaled → FVC reached
A missing plateau = incomplete exhalation or poor effort.
Fill-in-the-blank: The steeper the rise, the better the ______.
Effort
Steep rise = quick emptying of lungs.
What does it mean to superimpose flow-volume loops?
Plot multiple loops (predicted, pre-, and post-bronchodilator) on one graph
To compare performance and reversibility.
What does improvement in the post-bronchodilator loop suggest?
Reversible obstruction, as seen in asthma
Airways open better after medication.
If there’s little or no change between pre- and post-bronchodilator loops, what does it suggest?
A fixed obstruction such as COPD
Where airways don’t respond to bronchodilators.
Fill-in-the-blank: “Shift up = ______ up.” → What does this phrase help you remember?
opens up
The bronchodilator helped open airways.
What does a normal expiratory limb look like on a flow-volume loop?
It decreases in a linear or slightly concave fashion after a sharp rise to PEF.
After the first 25% of exhalation, what primarily determines airflow?
Airway resistance and elastic recoil (not effort).
Before 25% → effort dependent; after 25% → ______ dependent.
Effort-independent (depends on airway mechanics, not muscle effort).
Why do obstructive and restrictive diseases produce different FVL shapes?
Because they alter resistance and elastic recoil differently — obstruction changes flow rates; restriction reduces volumes.
What is the expected relationship between FEF₅₀% and FIF₅₀% in a normal test?
They should be about equal, or expiratory flow is slightly less than inspiratory.
What does the ratio FEF₅₀% / FIF₅₀% ≈ 1 indicate?
Normal airway function and good test quality.
What can a large difference between FEF₅₀% and FIF₅₀% suggest?
A large-airway obstruction (fixed or variable).