What is cellular respiration?
The process by which cells extract energy from food molecules to generate ATP.
What are the four stages of cellular respiration (in order)?
1) Glycolysis, 2) Pyruvate processing, 3) Citric acid cycle, 4) Electron transport and oxidative phosphorylation.
What is the overall chemical equation for cellular respiration?
C6H12O6 + 6 O2 → 6 CO2 + 6 H2O + ~36 ATP.
Where does cellular respiration occur in eukaryotes?
Cytoplasm (glycolysis) and mitochondria (remaining steps).
What is a redox reaction?
A reaction where electrons are transferred between molecules.
What is oxidation?
The loss of electrons.
What is reduction?
The gain of electrons.
What is NAD+?
An electron carrier that accepts electrons to become NADH.
What are two main electron carriers in cellular respiration?
NAD+/NADH and FAD/FADH2.
What does ATP stand for?
Adenosine triphosphate.
What happens during ATP hydrolysis?
ATP → ADP + Pi (exergonic reaction that releases energy).
What is phosphorylation?
Adding a phosphate group to a molecule.
What are the two types of phosphorylation that generate ATP?
Substrate-level phosphorylation and oxidative phosphorylation.
Where does glycolysis occur?
In the cytoplasm.
Is oxygen required for glycolysis?
No, glycolysis is anaerobic.
What are the inputs of glycolysis?
1 glucose, 2 NAD+, 2 ATP, 4 ADP.
What are the outputs of glycolysis?
2 pyruvate, 2 NADH, 4 ATP (net gain of 2 ATP).
What are the two phases of glycolysis?
Energy investment phase and energy payoff phase.
Where does pyruvate processing occur in eukaryotes?
Mitochondrial matrix.
What happens to pyruvate during this step?
One carbon is released as CO2, NADH is produced, and acetyl CoA is formed.
What enzyme complex catalyzes pyruvate oxidation?
Pyruvate dehydrogenase.
Where does the citric acid cycle occur?
In the mitochondrial matrix.
What molecule enters the citric acid cycle?
Acetyl CoA.
What are the outputs per turn of the cycle?
3 NADH, 1 FADH2, 1 ATP (or GTP), and 2 CO2.