What does pH measure?
The acidity or alkalinity of the blood
What does PaCO₂ measure?
The amount of carbon dioxide in the blood
What does PaO₂ measure?
The amount of oxygen in the blood
What does HCO₃⁻ represent?
The level of bicarbonate in the blood, helps maintain acid-base balance
What does SaO₂ represent?
The percentage of hemoglobin bound to oxygen
pH 7.30, PaCO₂ 50, HCO₃ 24
Respiratory acidosis
pH 7.45, PaCO₂ 38, HCO₃ 24
Normal
pH 7.18, PaCO₂ 18, HCO₃ 12
Metabolic acidosis + respiratory alkalosis (partial compensation)
pH 7.23, PaCO₂ 40, HCO₃ 16
Metabolic acidosis
pH 7.49, PaCO₂ 28, HCO₃ 18
Respiratory alkalosis + metabolic acidosis (mixed disorder)
pH 7.55, PaCO₂ 40, HCO₃ 35
Metabolic alkalosis
pH 7.20, PaCO₂ 30, HCO₃ 35
Partially compensated metabolic acidosis
pH 7.35, PaCO₂ 60, HCO₃ 25
Uncompensated respiratory acidosis
If a patient is hyperventilating, how would ABG change?
↓ CO₂ → Respiratory alkalosis
In a patient with COPD, what might you expect on ABG?
↑ CO₂, ↓ pH (respiratory acidosis), possible compensation with ↑ HCO₃
What is compensation?
Body’s way of fixing pH imbalances
How do lungs compensate for metabolic problems?
Blow off or retain CO₂ (fast: minutes–hours)
How do kidneys compensate for respiratory problems?
Hold onto or excrete bicarbonate (slow: hours–days)
What is uncompensated?
pH abnormal, one system abnormal, other system normal (no help yet)
What is partially compensated?
pH abnormal, both CO₂ & HCO₃ abnormal (other system trying)
What is fully compensated?
pH normal, both CO₂ & HCO₃ abnormal (balance restored)
pH 7.28, PaCO₂ 50, HCO₃ 24
Uncompensated respiratory acidosis
pH 7.48, PaCO₂ 32, HCO₃ 23
Respiratory alkalosis
pH 7.34, PaCO₂ 50, HCO₃ 30
Partially compensated respiratory acidosis