What are the most common inflammatory conditions of the brain and spinal cord?
Brain abscesses, meningitis, encephalitis.
What is meningitis?
Acute inflammation of the meningeal tissues surrounding the brain and spinal cord.
What are the causes of meningitis?
Bacteria, viruses, fungi, chemicals.
When is meningitis most common?
Fall, winter, early spring.
Who is at higher risk for meningitis?
College students (dorms), older adults, institutionalized people (prison, nursing homes, group homes).
How is meningitis spread?
Highly spreadable; occurs often when people are in close quarters (e.g., sneezing season).
What is the general mortality rate for meningitis?
10–15%; higher in older adults and immunocompromised.
What are potential long-term complications of meningitis?
Long-term neurological deficits.
Most common bacterial causes of meningitis?
Streptococcus pneumoniae, Neisseria meningitidis (covered in vaccines).
How do bacteria enter the CNS?
Via upper respiratory tract, bloodstream, penetrating skull wounds, fractured sinuses, or basilar skull fracture.
What does inflammation cause in bacterial meningitis?
↑ CSF production → ↑ ICP; purulent secretions spread through CSF.
What happens if infection spreads to brain parenchyma or concurrent encephalitis occurs?
Cerebral edema and significantly ↑ ICP.
Key clinical signs of bacterial meningitis?
Fever, severe headache, N/V, nuchal rigidity (physical inability to flex neck).
Additional signs of bacterial meningitis?
Photophobia, decreased LOC, signs of ↑ ICP, petechiae (trunk, extremities, mucous membranes).
Do viral meningitis symptoms differ from bacterial?
No, symptoms are the same.
Diagnostics for bacterial meningitis?
CBC, coag studies, CMP, blood cultures, lumbar puncture (LP) with CSF analysis (protein, WBC, glucose, gram stain, culture), CT head.
How is meningitis treated until proven otherwise?
Assume bacterial and treat empirically.
Purpose of LP?
Measure ICP; collect CSF for cultures/cytology; infuse chemo, anesthetics, meds; inject contrast for CNS imaging.
Nursing role in LP?
Educate, support, prep patient.
Position for LP?
Hunched sitting or lying on side bent over (between L3–L4).
Post-LP care?
Lie flat at least 60 min; patch site; monitor for CSF leak (headache).
Non-pharmacologic treatment for bacterial meningitis?
Rest, IV fluids, hypothermia.
Pharmacologic treatment for bacterial meningitis?
IV antibiotics (ampicillin, penicillin, cephalosporin), codeine (HA), dexamethasone (steroid), Tylenol (fever), IV phenytoin (seizure prevention if high risk).
Why start antibiotics even if meningitis type is unknown?
If it is bacterial and treatment is delayed, the patient could die