ABX THERAPY

Question 1

sulfonamides

• sulfamethoxazole
• sulfisoxazole
• sulfadiazine

trimethoprine

Answer 1

folic acid synthesis and reduction

Question 2

daptomycin (gram +)

polymyxsin (gram -)

Answer 2

membrane integrity

Question 3

glycopeptides

• vancomycin
• bacitracin

Answer 3

cell wall synthesis

-peptidoglycan synthesis

Question 4

penicillinase-sensitive penicillins

penicillinase resistant penicillins

antipseudomonal

cephalosporins

carbapenems

monobactams

Answer 4

peptidoglycan cross linking

Question 5

metronidazole

Answer 5

DNA integrity (free radicals)

Question 6

rifampin

Answer 6

mRNA synthesis (rifampin)

Question 7

fluorquinolones

• ciprofloxacin
• levofloxacin

quinolone
-nalidixic acid

Answer 7

gyrase

Question 8

chloramphenicol
clindamycin
linezolid
macrolides
streptogramins

Answer 8

protein synthesis

-50s subunit

Question 9

aminoglycosides
glyclcycline
tetracyline

Answer 9

protein synthesis

-30s subunit