BIOLOGIC AGENTS

Question 1

Monoclonal antibodies-target over expressed cell surface receptors

• ximab
• zumab
• umab

Answer 1

chimeric human mouse MAB, rituximsb
humanized mouse MAB, bevacizumab
human MAB, denusomab

Question 2

small molecule inhibitors-target intracellular molecules

• tinib
• zomib
• ciclib

Answer 2

tyrosine kinase inhibitor, imatinib
proteasome inhibitor. bortezomib
cyclin dependent kinase inhibitor, palbociclib

Question 3

receptor fusion proteins

-cept

Answer 3

TNF alpha antagonist, etanercept

Question 4

interleukin receptor modulator (-kin) agonists and antagonist of interleukin receptors

• leukin
• kinra

Answer 4

IL-2 agonist/analog, aldesleukin

interleukin receptor antagonist, anakinra