pituitary tumours
growth
insulin-like growth factor-1
akroparastheasia
after
before = gigantism
T
glucose
glucose
GH
IGF-1
OGTT
> 1microg/L
MRI of head
visual field
trans-sphenoidal surgery
Somatostatin (SSA) IM
e.g. -reotide (octreotide)
GH antagonist
Pegmisovant
Pegmisovant
50%
growth (hands, feet, jaw)
coarse face (wide nose)
pituitary mass signs
laryngeal dyspnoea (fixed cords)
DM increases risk of IHD