excess aldosterone secretion by adrenal
independent of renin-angiotensin
sodium retention
water retention
hypokalaemia
solitary aldosterone producing adenoma (2/3rds)
T
ACTH regulatory element associates with aldosterone synthase enzyme bringing aldosterone production under the control of ACTH
laparoscopic adrenalectomy
Spironolactone
spironolactone
Spironolactone
eplerenone
Dexamethasone 1mg/24 hours
decreased renal perfusion (stenosis)
diuretics
Na Cl leak in loop of henle
volume depletion
increased Renin