Effects of aging on cardiovascular structure and function (4)
Increased vascular and myocardial stiffness
Decreased ß-adrenergic and baroreceptor responsiveness
Impaired sinus node function
Impaired endothelial function
Net effect = large reduction in cv reserve
Clinical implications of the effects of aging on the cardiovasc system (4)
Increased SBP and pulse pressure
Increased prevalence Afib,HF esp with preserved LV function
Increase prevalence of bradyarrythmias and “sick sinus syndrome”
Worse prognosis associated with all CV disease