lifetime prevalence of alcohol abuse
18%
each drink raises BAL about 0.015 to 0.020
0.015 to 0.020
legally intoxicated
0.080
alcohol dependence
chronic exposure –>changes perm of cell membrane–>down regulates GABA and upregulates glutamate
cessation= net excitation
what do you use for someone in alcohol withdrawal
benzos because they are cross-tolerant- two substances that brain treats the same way
2 endocanabinoid R
CB1-in brain
CB2-immune tissues
the good part of marijuana
cannabidiol