Aldosterone pathway

Question 1

Stimulus for aldosterone pathway

Answer 1

ANG II, decrease Na+ levels, increased K+ levels

Question 2

What receptors sense the above stimuli?

Answer 2

Adrenal cortex receptors

Question 3

Response of adrenal cortex?

Answer 3

Release aldosterone into the blood

Question 4

Where does aldosterone bind?

Answer 4

Tubules in kidneys

Question 5

Effects of aldosterone on kidneys

Answer 5

Increases Na+/H2O absorption -> increases blood volume/pressure
Decreases Na+/H2O lost in urine ->decrease K+ in plasma
Principle cells in collecting duct increase K+ secretion -> decreases K+ in plasma

Question 6

Net effect of aldosterone?

Answer 6

Increase Na+ levels
Decrease K+ levels
Maintain blood volume
BP at homeostasis

Question 7

Feedback loop?

Answer 7

Negative feedback loop