Alpha Blockers

Question 1

Nonselective blockers?

Answer 1

1) Phenoxybenzamine (irreversible)

2) Phentolamine (reversible)

Question 2

A1 selective?

Answer 2

-osin ending

Question 3

A2 selective?

Answer 3

Mirtazapine

Question 4

Uses for phenoxybenzamine?

Answer 4

Pheochromocytoma (used before tumor removal since high levels of release catecholamines will not be able to overcome blockage)

Question 5

Uses for phentolamine?

Answer 5

Give to pts on MAOIs who eat tyramine-containing foods

Question 6

Uses for a1-blockers?

Answer 6

HTN and urinary retention in BPH

Question 7

Use for mirtazapine?

Answer 7

Depression

Question 8

AEs of phenoxybenzamine?

Answer 8

1) Orthostatic hypotension

2) Reflex tachycardia

Question 9

AEs of a1 blockers?

Answer 9

1) 1st dose orthostatic hypotension!!!!

2) Dizziness and HA

Question 10

AEs of mirtazapine?

Answer 10

Sedation, high cholesterol, increased appetite (Makes you Munch!)