What resembles the substrate?
Competitive inhibitors
Which inhibitor is overcome by increasing the substrate?
Competitive inhibitors
Which inhibitor binds to the active site?
Competitive inhibitors
Competitive inhibitors’ effect on Vmax?
Unchanged
Noncompetitive inhibitors’ effect on Vmax?
Decreased
Competitive inhibitors’ effect on Km?
Increased
Noncompetitive inhibitors’ effect on Km?
Unchanged
Pharmacodynamics of competitive inhibitors?
Decreases potency (shifts curve left)
Pharmacodynamics of noncompetitive inhibitors?
Decreases efficacy (shifts curve down)