AML (Subgroups table) Flashcards

(30 cards)

1
Q
  1. What is AML M0 also called?
A

AML minimally differentiated

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2
Q
  1. In AML M0 what are the results for MPO and SBB?
A

Both negative

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3
Q
  1. What is AML M1 also called?
A

AML without maturation

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4
Q
  1. What distinctive feature may be seen in AML M1?
A

Auer rods

linear projections of primary granules

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5
Q
  1. What is AML M2 also called?
A

AML with maturation

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6
Q
  1. What is the most common subtype of AML?
A

AML M2

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7
Q
  1. What distinctive feature may be seen in AML M2?
A

Auer rods

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8
Q
  1. What is AML M3 also called?
A

Acute Promyelocytic Leukemia APL

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9
Q
  1. Which AML is associated with disseminated intravascular coagulation DIC?
A

AML M3

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10
Q
  1. What abnormal white blood cells with bundles of Auer rods are seen in AML M3?
A

Faggot cells

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11
Q
  1. What are the nuclear shapes characteristic of AML M3 microgranular variant M3V?
A

Butterfly
Bowtie
Coin on coin
Apple core

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12
Q
  1. What is AML M4 also called?
A

Acute Myelomonocytic Leukemia AMML

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13
Q
  1. What is another name for AML M4?
A

Naegeli Monocytic Leukemia

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14
Q
  1. What is the second most common AML subtype?
A

AML M4

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15
Q
  1. What variant of AML M4 shows increased marrow eosinophils?
A

AML M4E

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16
Q
  1. What is AML M5 also called?
A

Acute Monocytic Leukemia AMoL

17
Q
  1. What is another name for AML M5?
A

Schilling Leukemia

18
Q
  1. What subtype of AML M5 is seen in children with more than 80 percent monoblasts in the bone marrow?
A

AML M5a poorly differentiated

19
Q
  1. What subtype of AML M5 is seen in middle aged adults with less than 80 percent monoblasts in the bone marrow?
A

AML M5b well differentiated

20
Q
  1. What is AML M6 also called?
A

Acute Erythroleukemia

21
Q
  1. What is another name for AML M6?
A

DiGuglielmo’s Syndrome

22
Q
  1. What type of anemia is typical in AML M6?

significant

A

Macrocytic normochromic anemia

23
Q
  1. What type of anemia is most common in AML in general?
A

Normocytic normochromic anemia

24
Q
  1. In AML M6 what is the PAS result for erythroid cells?
A

Strongly positive

25
25. In normal erythroid cells what is the PAS result?
Negative
26
26. What is AML M7 also called?
Acute Megakaryocytic Leukemia
27
27. What stain is used to confirm AML M7?
Factor VIII immunocytochemical stain
28
28. What is AML M8 also called?
Acute Basophilic Leukemia
29
29. Which AML subgroups may demonstrate Auer rods?
M1 M2 M3 M4 and M6
30
30. Which leukemias are PAS positive?
ALL L1 ALL L2 and AML M6