Antidepressants

Question 1

What three neurotransmitters are involved in depression?

Answer 1

• Serotonin
• Norepinephrine
• Dopamine

Question 2

The __________ has long been implicated in the structural neuropathology of depression and response to stress.

Answer 2

hippocampus

Question 3

Depression is associated with hippocampal _______.

Answer 3

atrophy

Question 4

Atrophy of the ________ correlates with the duration of depression.

Answer 4

Hippocampus

Question 5

Emerging data correlates remission of depression with restoration of normal _______ volume

Answer 5

hippocampal

Question 6

What is the only SRI with a really long half life (2-3 days)?

Answer 6

Fluoxetine (Prozac)

Question 7

What are the indications for ECT?

Answer 7

• Major depressive disorder
• Manic episodes
• Malignant catatonia (schizophrenia)

**chronic schizophrenia is not treated