Antineoplastic

Question 1

therapeutic actions Methotrexate

Answer 1

breast cancer

Rheumatoid arthritis

Question 2

mechanism of action Methotrexate

Answer 2

S-phase cell-cycle-specific antimetabolite

Immunosuppressants in autoimmune disorders, such as rheumatoid arthritis

Question 3

adverse effects Methotrexate

Answer 3

bone marrow suppression
immunosuppression
alopecia

Question 4

contraindications Methotrexate

Answer 4

gout

dehydrated patients

Question 5

drug interactions Methotrexate

Answer 5

alcohol

Question 6

therapeutic actions Anastrozole

Answer 6

post menopausal breast cancer

Question 7

mechanism of action Anastrozole

Answer 7

Anastrozole stops the body from producing estrogen, causing the metastatic tumours to die.
By stopping estrogen production, the recurrence risk of these tumours is much smaller.