therapeutic actions biphosphonates
postmenopausal osteoporosis
mechanism of action biphosphonates
decreases fracture rate and increases bone mineral density due to the binding of biphosphonates to mineralised bone.
powerful suppressors of osteoclastic-mediated bone erosion and resorption.
adverse effects biphosphonates
headache
rash
osteomalacia (softening of bones)
contraindications biphosphonates
osteomalacia (softening of bones)
pregnancy
drug interaction biphosphonates
NSAIDS (non steroidal anti inflammatory drugs)