Antipsychotics

Question 1

brand name and class

generic: aripiprazole

Answer 1

brand: abilify
class: second generation antipsychotic

Question 2

generic name and class

brand: latuda

Answer 2

generic: lurasidone
class: second generation antipsychotic

Question 3

brand name and class

generic: olanzapine

Answer 3

brand: zyprexa
class: second generation antipsychotic

Question 4

generic name and class

brand: seroquel, seroquel xr

Answer 4

generic: quetiapine
class: second generation antipsychotic

Question 5

brand name and class

generic: risperidone

Answer 5

brand: risperidal
class: second generation antipsychotic

Question 6

generic name and class

brand: geodon oral

Answer 6

generic: ziprasidone
class: second generation antipsychotic

Question 7

MOA for SGA

second generation antipsychotics

Answer 7

combination of dopamine antagonism and serotonin actions which are variable. Some are partial agonists of dopamine

Question 8

BBW

latuda, risperidal, geodon oral

Answer 8

increased mortality in elderly patients with dementia-related psychosis

Question 9

BBW

abilify, zyprexa, seroquel

Answer 9

• increased mortality in elderly patients with dementia-related psychosis
• increased risk of suicidal thinking and behavior in children, adolescents and young adults

Question 10

ADRs for SGAs

Answer 10

• metabolic (lipids, glucose, weight gain)
• orthostatic hypertension
• dystonia, pseudoparkisonism, akathisia
• sedation
• QTc

Question 11

key counseling points

all SGAs

Answer 11

• do not drive or operate machinery when taking first dose until you know how med will make you feel
• if med makes you drowsy take at bedtime. if med makes you restless take in morning w/o regard to food at either time of day
• do not take other meds w/o checking with MD or RPh
• avoid alcohol and recreational substances
• take med as prescribed