ApLs

Question 1

Treatment for asymptomatic patients with APLs

Answer 1

No therapy

Question 2

High risk situations

• Surgery
• long term mobilization

Answer 2

Low MW heparin

Question 3

Persistent multiple APL + patient

Answer 3

• Consider low dose aspirin

Question 4

Definite APS and first venous thromboembolism

Answer 4

• Long term anticoag

- INR 2-3

Question 5

Definite APS and first arterial thromboembolism

Answer 5

• Long term anticoag or combined anti coag and anti aggregation
• INR 3-4

Question 6

Definite APS and recurrent thrombosis despite oral anti coag with target INR 2-3

Answer 6

• Target INR 3-4

- ALternative therapies such as extended therapeutic dose of LMWH