What is RA
Autoimmune disease
Chronic inflammation of joints
Complex disease with no cure
What factors are involved in RA
Rheumatoid factor
- autoantibodies against IgG
Anti-citrullinated protein antibodies (ACPA’s)
What are the normal function of synovium
Lubrication of cartilage surfaces
Provide nutrients to cartialge
What drugs can you use for symptomatic relief
NSAIDs
Steroidal drugs
What drugs can you use to modify the disease (DMARD)
csDMARD
tsDMARD
bDMARD