Appetite
“drive to eat”
Hunger
often used interchangeably with appetite, but more the perception and manifestation of appetite/drive to eat.
satiation
perception of process leading to the termination of eating
satiety
the feeling of fullness after eating
Orexigenic
appetite-stimulating
Anorexigenic
appetite suppressing
what does hedonic eating mean ?
Sense of emotional attachment to food and how they make us feel
eating for pleasure (taste, cravings), not because you’re physically hungry.
whats leptin ?
what does homeostatic eating mean
eating because your body needs energy, not for pleasure.
This is driven by hormones like:
Ghrelin → tells you you’re hungry
Leptin, PYY, GLP-1 → signal fullness
name the two metabolic signals
leptin and ghrelin
How does leptin work ?
This normally leads to:
Reduced appetite (it is anorexigenic, the opposite of orexigenic)
Increased energy
whats leptin resistance ?
Many people with obesity actually have high leptin levels, but the brain stops responding to it — this is called leptin resistance.
When the brain doesn’t “see” the leptin:
Appetite stays high
Metabolism may slow
Weight becomes harder to regulate
whats ghrelin ?
When ghrelin levels rise its stimulates the hypothalamus in brain to :
Increase appetite
Make food seem more rewarding
name the two gut hormones/ Episodic signals which reduce hunger
Peptide tyrosine-tryosine ( PYY )
and
Glucagon-like peptide 1 ( GLP-1 )
whats Peptide tyrosine-tryosine ( PYY )
Anorexigenic hormone
Secreted from ilium in the stomach and the large intestine while feeding.
Once in the bloodstream, it travels to the hypothalamus and:
Decreases appetite
Slows gastric emptying (food stays in the stomach longer)
Reduces food intake overall
whats Glucagon-like peptide 1 ( GLP-1 )
Anorexigenic hormone
Secreted from the ileum and large intestine with feeding
Reduces hunger, slows digestion, and helps regulate blood sugar.
Basis for several modern weight-loss medications.
what do different macronutrients do to the ghrelin hormone ?
fat - weak suppress ability
protein - suppresses to greatest extent
CHO - biphasically = first a quick spike, then a slower, sustained release.
what impact does exercise have on ghrelin ?
exercise causes ghrelin to drop, delaying feeding
due to reduced blood supply and lactic accumulation making it feel as if its not time to eat
will increase hunger later in day