Autoimmune Hepatitis

Question 1

Autoimmune Hepatitis Type 1 antibody

Answer 1

Anti ANA
Anti SMA ( against actin )
Anti-soluble liver antigrn
Atypical p-ANCA ( x-ANCA )
young female

Question 2

Autoimmune Hepatitis Type 2 antibody

Answer 2

Anti LKM1
Anti Liver cytosol 1 antibody
child

Question 3

Anti LKM1 seen in

Answer 3

HCV

Question 4

Anti LKM2 seen in

Answer 4

Drug induced hepatitis

Question 5

Anti LKM3 seen in

Answer 5

HDV

Question 6

Dx of Autoimmune Hepatitis

Answer 6

LFT
Albumin decrease gamma globulin increase
Viral hepatitis
PT increase
RA factor +
ANA + , Anti SMA , Anti LKM1 , Liver cytosol 1 antibody
Liver biopsy : INTERFACE HEPATITIS
ROSETTE FORMATION ( regeneration of new heapatocyte )

Question 7

Mx of Autoimmune Hepatitis

Answer 7

steroid + Azathioprine

Question 8

x-ANCA seen in

Answer 8

Autoimmune Hepatitis Type 1

Question 9

c-ANCA seen in

Answer 9

Wegner’s granulomatosis / Granulomatosis with polyangiitis

Question 10

p-ANCA seen in

Answer 10

Microscopic polyangiitis & Churg Strauss syndrome

Question 11

which disease has propensity to reoccur in transplanted liver

Answer 11

Autoimmune Hepatitis