B6.020 Large Group

Question 1

risk of child having DM with a mother with DM

Answer 1

Autosomal Dominant - 50%

extent of repeat expansion in child compared to mother is an important determinant in severity

Question 2

approach to delivery of a child with suspected DM

Answer 2

pre-natal genetic testing
no treatment of underlying disease, but newborn will have to be quickly assessed and be quickly treated if disease is severe
perinatal mortality is high for congenital DM