B6.035 HSP

Question 1

first step in pt management when presenting w palpable purpura

Answer 1

CBC - rule out other causes

Question 2

bad signs for HSP prognosis

Answer 2

older pt
HTN at onset
crescent on biopsy

Question 3

why not use NSAIDs in HSP?

Answer 3

bleeding (platelet inhibition)
exacerbate GI symptoms
kidney injury

Question 4

does HSP involve lungs?

Answer 4

no

anti-GBM does

Question 5

organ specific autoimmune disease

Answer 5

autoantibodies directly bind to and injure target organs

Question 6

systemic autoimmune diseases

Answer 6

autoantibodies react with free molecules and cell surface and nucleoprotein antigens, forming immune complexes