Dermatophilus congolensis key attributes
Gram positive, actinomycete
Key gross with dermatophilosis
Chronic superficial exudative dermatitis on dorsum (paintbrush lesions)
Key histo with dermatophilosis
Thick, laminar crusts with alternating orthokeratotic/parakeratotic hyperkeratosis and inflammation, with bacterial filaments formed by parallel rows of coccoid zoospores (train tracks)
Staph aureus key attributes
Gram positive cocci
Key gross with botryomycosis
Nonpruritic nodules, may have draining tracts
Key histo with botryomycosis
Tissue grains- radiating clubs of amorphous eosinophilic material (Splendore-Hoeppli) centered on colonies of bacteria
Cause of feline leprosy
Mycobacterium lepraemurium
Reservoir and unique feature of mycobacterium leprae
Armadillos; Nerve involvement
Best stain for mycobacterium
Fite Faraco (modified AF)
Nocardia spp. attributes; virulence factors
Gram-positive actinomycetes, branching filamentous, variably acid-fast (only FF); complex cell wall lipids, resistance to phagocytosis
Classic gross with nocardia
Reddish-brown cavitary exudate, sulfur granules usually absent
Actinomyces spp. attributes
Gram-positive actinomycetes, NON acid-fast, filamentous, are commensals
Clinical presentation with actinomyces
Lumpy jaw in cattle, poll evil, fistulous withers in horses
Gross lesions with actinomyces spp.
Often see sulfur granules
Features of erysipelothrix rhusiopathiae
Small gram positive bacillus
Three forms of erysipelas and skin lesions in each
Acute- very sick, blue-purple lesions on legs, abdomen, and ears
Subacute- not sick, erythematous papules and wheals forming diamonds
Chronic- necrosis and sloughing of skin lesions, ulcers
Key histo with erysipelas
Neutrophilic vasculitis, cutaneous necrosis, suppurative hydradenitis
What causes gram negative sepsis associated skin lesions in pigs? Gross findings?
Salmonella cholerasuis
Pasteurella multocida
E. Coli, shiga toxin 2e producing (edema disease)
Blue-purple discoloration of skin on ears, abdomen, snout, tail
Features of staphylococcus hyicus; disease caused?
Gram positive, colony forming cocci; exudative epidermitis
What causes turkey egg kidney in pigs?
Erysipelas, CSF, ASF, S.cholerasuis, S.typhisuis, PVC-2
Age of piglets affected by greasy pig dz
Piglets 5-35 days
Toxins produced by staph hyicus; mechanism of action
Exfoliative toxins- ExhA-D, SHETA-B; digest desmoglein-1 in epidermis
Three forms of greasy pig disease
Acute form- sudden skin lesions, greasy brown exudate, erosions, conjunctivitis
Subacute form- drawn out, thickened wrinkled skin, dry, hard, cracked with red furrows
Chronic- milder, confined to head and ears
Key histo with greasy pig disease
Subcorneal vesicular to pustular dermatitis early
Eventually, thick crusts of orthokeratotic and parakeratotic hyperkeratosis, neutrophils and colonies of cocci
