Body Logistics

Question 1

What is Marfan’s syndrome?

Answer 1

• Autosomal dominant disorder in which expression of the fibrillin gene is abnormal –> elastic tissue is abnormal.
• Sufferers are abnormally tall, exhibit arachnodactyly (long fingers), have frequent joint dislocation and can be at risk of catastrophic aortic rupture.

Question 2

What are the two types of osteoporosis?

Answer 2

Type 1 - post-menopausal women - increase in osteoclast number with oestrogen withdrawal

Type 2 - elderly men and women - attenuated osteoblasts function