List 7 non-pharm management of BPSD?
Interdisciplinary approach
Music therapy
Massage therapy
Robotic pets
Animal therapy
Physical exercise
Aromatherapy
List 4 second line pharm management of BPSD?
Quetiapine
Haloperidol (2-6 mg/d)
Nabilone
Carbamazepine
10 BPSD behaviours that do NOT involve psychosis/affective symptoms
Arguing
Hoarding
Pacing
Wandering
Rummaging
Rejection of care
Worrying
Shadowing (following caregiver)
Socially inappropriate behaviour
Sexually inappropriate behaviour
Waking at night
4 ways to identify pain in a patient with severe dementia
-Facial expressions (grimacing, brow lowering, closed eyes, wincing, mouth opening)
-Vocalisations/verbalizations (moaning, groaning, grunting, crying, oww, gasping)
-Body movements (flinching, thrashing, rocking, bracing, rubbing, limping, clenched fists, shaking)
-Changes in interpersonal interactions (not wanting to be touched, decreased interaction, difficult to console)
-Change in activity patterns/ routines
Mental status change
12 components of the NPI?
delusions
hallucinations
agitation/aggression
depression/dysphoria
anxiety
elation/euphoria
apathy/indifference
disinhibition
irritability/lability
aberrant motor behaviour
sleep and nighttime behaviours
appetite changes
List 8 communication strategies for patient with agitation
Use the person’s name
Speak slowly and clearly
Use simple sentences
Ask yes/no questions
Use one step instructions
Use positive statements
Avoid arguing
Accept different perceptions of time and reality
Avoid confrontation or correction.
Reassurance, distraction, and validation of the person’s feelings
List 10 ways to tell a caregiver how to manage wandering
-Look for pattern
-Keep objects associated with the outdoors (car keys, jackets, shoes) out of the person’s view
-Re-locate door locks above eye level or where the person can’t see them
-Try disguising doors
-Alarms
-Door mats that set off an alarm when stepped on
-Engage in regular physical activity
-Tell neighbours, nearby businesses and your local police
2 categories of wanderers
Random wandering (moves aimlessly with no apparent goal, often in response to anxiety or physical discomfort)
Goal directed wandering (purposeful, often in response to a concern/worry or past obligations such as going to work or making supper)
Pharm management of apathy?
Methylphenidate 5mg PO daily
Modafinil - no significant difference
4 features of the Charles Bonnet syndrome
Well formed
Vivid, elaborate
Often stereotyped visual hallucinations
Maintain insight that the hallucinations are not real
Visual hallucination only
5 causes of tardive dyskinesia
antipsychotics
antiemetics
antiepileptics
antidepressants: trazodone, fluoxetine, doxepin, clomipramine, amitriptyline
lithium
MOAB-i
2 non-pharm and 3 pharm treatments of tardive dyskinesia?
Non-pharm:
1. Stop offending agents (works in 13%)
2. DBS (globus pallidus/STN)
Pharm:
1. Valbenazine (VMAT2) / tetrabenazine (VMAT2)
2. Clonazepam
3. Amantadine
4 risk factors that predispose towards hoarding behaviour in an older adult
Social isolation
Past trauma
Depression and anxiety, Personality disorders, PTSD
Cognitive deficits (memory, attention, executive function)
Substance use disorders
6 actions you can take to help family of patient with BPSD?
Referral to Behaviour Support Outreach Team
Psychosocial and psychoeducational interventions for caregivers (CCCDTD5)
Connection to organizations for dementia for resources and support (e.g., Alzheimer Society) (CCCDTD5)
Case management (CCCDTD5)
Connection to homecare services
Referral to adult day programs and other respite programs
4 domains of Mild Behaviour Impairment (MBI)
IDEAS
1) impulse dyscontrol
2) decreased motivation
3) emotional dysregulation
4) abnormal perception or thought content
5) social inappropriateness
What is a validated tool for MBI?
MBI Checklist (Ismail 2017)
What is the relative risk for mortality with the use of atypical antipsychotics for BPSD? Other than stroke and mortality, what are three other risks associated with their use?
Mortality RR: 1.6 (1.5-2)
EPS, NMS, sedation, weight gain
● Olanzapine RR = 2.31
● Aripiprazole RR = 1.99
● Quetiapine RR = 1.86
● Risperidone RR = 1.35
6 triggers for new-onset BPSD that are not disease- or medication-related