What is bronchiolitis?
Bronchiolitis is an acute inflammatory condition of the bronchioles, most commonly affecting infants, leading to lower respiratory tract infection.
What is the most common causative organism of bronchiolitis?
Respiratory syncytial virus (RSV), responsible for approximately 75–80% of cases.
Which age group is most commonly affected by bronchiolitis?
Infants under 1 year of age, particularly those aged 1–9 months, with peak incidence at 3–6 months.
Why are newborns relatively protected from RSV infection?
Maternal IgG antibodies provide passive protection in early life.
When is bronchiolitis most commonly seen?
During the winter months.
What other pathogens can cause bronchiolitis?
Mycoplasma and adenoviruses; secondary bacterial infection may occur.
Which children are at higher risk of severe bronchiolitis?
Premature infants, those with bronchopulmonary dysplasia, congenital heart disease, or cystic fibrosis.
What symptoms typically precede the onset of bronchiolitis?
Coryzal symptoms such as runny nose and mild fever.
What are the typical respiratory features of bronchiolitis?
Dry cough, increasing breathlessness, wheeze, and fine inspiratory crackles (which may not always be present).
Why do infants with bronchiolitis often require hospital admission?
Feeding difficulties due to increasing respiratory distress are a common reason for admission.
What features mandate immediate hospital referral according to NICE?
Apnoea, appearing seriously unwell, severe respiratory distress, central cyanosis, or persistent oxygen saturations below 92% in air.
What signs indicate severe respiratory distress in bronchiolitis?
Grunting, marked chest recession, or respiratory rate over 70 breaths per minute.
When should clinicians consider hospital referral for bronchiolitis?
Respiratory rate over 60 breaths per minute, poor feeding (50–75% of normal intake), or clinical dehydration.
What investigation may confirm RSV infection?
Immunofluorescence testing of nasopharyngeal secretions.
Are routine investigations usually required in bronchiolitis?
No, bronchiolitis is a clinical diagnosis and investigations are rarely needed.
What is the mainstay of management for bronchiolitis?
Supportive care.
When should oxygen be given in bronchiolitis?
If oxygen saturations are persistently below 92% on room air.
How is oxygen typically delivered to infants with bronchiolitis?
Humidified oxygen via a head box.
When is nasogastric feeding indicated in bronchiolitis?
If the infant is unable to maintain adequate oral intake due to respiratory distress.
What role does suction play in bronchiolitis management?
It may be used to clear excessive upper airway secretions.
Are bronchodilators, steroids, or antibiotics routinely indicated in bronchiolitis?
No, they are not routinely recommended unless there is another indication.
What is the overall prognosis of bronchiolitis?
Most infants recover fully with supportive care, although symptoms may last several weeks.