What is cellulitis?
Cellulitis is an acute bacterial infection of the dermis and subcutaneous tissue causing inflammation of the skin and systemic illness.
Which children are at increased risk of developing cellulitis?
Children with eczema or other skin conditions, immunodeficiency, diabetes, obesity, athlete’s foot, or breaches in the skin barrier.
Which organisms most commonly cause cellulitis?
Streptococcus species and Staphylococcus species, with Streptococcus pyogenes being the most common cause.
How do bacteria typically enter the skin in cellulitis?
Through breaches in the skin barrier such as trauma, scratches, insect bites, ulcers, or pre-existing skin disease.
What are the typical skin features of cellulitis?
Erythema, swelling, warmth, tenderness, and poorly demarcated margins.
What systemic features may be present in cellulitis?
Fever, malaise, and regional lymphadenopathy.
What key feature helps distinguish cellulitis from erysipelas?
Cellulitis has poorly defined margins, whereas erysipelas has well-defined, raised borders and more superficial involvement.
What features raise concern for necrotising fasciitis rather than cellulitis?
Severe pain out of proportion to examination, rapidly spreading erythema, systemic toxicity, crepitus, and skin necrosis.
How can cellulitis be differentiated from contact dermatitis?
Contact dermatitis is itchy, often bilateral, linked to an identifiable trigger, and lacks systemic features.
When should septic arthritis or osteomyelitis be considered instead of cellulitis?
When there is focal joint or bone pain, reduced joint movement, or an effusion with overlying erythema.
What bedside assessments are performed in suspected cellulitis?
Observations including temperature, heart rate, and assessment for systemic illness.
Which blood tests are useful in cellulitis?
Full blood count and CRP to assess inflammation, and blood cultures if systemic infection is suspected.
When is imaging indicated in cellulitis?
If an abscess, deep infection, or osteomyelitis is suspected, or if there is poor response to treatment.
When should a skin swab be taken in cellulitis?
If there is a wound, ulcer, or discharge to guide antibiotic choice.
How is cellulitis treated?
With oral or intravenous antibiotics depending on severity, commonly flucloxacillin or cephalosporins, with clindamycin as an alternative.
What conservative measures should be used alongside antibiotics?
Analgesia, elevation of the affected limb, and marking the area of erythema to monitor spread.
When is intravenous antibiotic therapy indicated in cellulitis?
In severe infection, systemic illness, immunocompromised patients, or failure of oral therapy.
When is surgical management required in cellulitis?
If there is abscess formation, necrosis, or failure to respond to medical treatment.
What complications can arise from cellulitis?
Abscess formation, necrotising fasciitis, osteomyelitis, sepsis, and streptococcal toxic shock syndrome.
What is the prognosis of cellulitis?
Most cases respond well to antibiotics with full recovery.
How can recurrence of cellulitis be reduced?
By treating underlying skin conditions, preventing skin breaks, and managing risk factors.