Campylobacter

Question 1

General characteristics

Answer 1

• spiral
• microaerobic
• GN
• cause gastroenteritis in people and animals

Question 2

_____ and _____ have the highest prevalence and disease impact

Answer 2

C. jejuni or C. coli (both are thermophilic)

• GI disease leading to diarrhea
• found in contaminated poultry meat

Question 3

Proliferative bowel disease in pig, horses, ferrets, and hamsters is caused by

Answer 3

Lawsonia intracellularis

Question 4

Swine dysentery

Answer 4

Caused by Treponema hyodysenteriae

- was once associated with campylobacter

Question 5

Transmission

Answer 5

Fecal oral or food/waterborne

Question 6

Zoonotic transmission

Answer 6

In meat from animal (chicken primarily)

- food safety issue

Question 7

Chemotaxis mechanisms

Answer 7

• flagellin sense chemotaxins for C. jejuni

- muscin, bile, and L-fucose are positive chemotaxins

Question 8

Cytotoxicity

Answer 8

Cytolethal distending toxin

• stops cell’s growth cycle in G2 = death
• cell death is the reason for blood in host diarrhea

Question 9

Clinical signs in dogs

Answer 9

Mucus-laden, watery, and/or bile streaked diarrhea that typically lasts 3-7 days
- diarrhea is a result of bacteria’s colonization in the intestine and cell death is due to cytolethal toxin

Question 10

What is the standard method of diagnosis?

Answer 10

Microaerobic culture of feces at 42 C

Question 11

Thermophilic/thermotolerant Campylobacter spp. include:

Answer 11

• C. jejuni
• C. coli
• C. upsaliensis
• C. mucosalis
• C. hyointestinalis
• C. helveticus
• –> all grow best at 42 C, but are capable of growth at 37 C

Question 12

C. fetus

Answer 12

Do not grow well at 42 C

Question 13

C. jejuni is differentiated on its ability to ______

Answer 13

Hydrolyze hippurate

Question 14

What is the drug of choice for Campy in humans?

Answer 14

Erythromycin

- is also effective in other animals

Question 15

Bovine genital campylobacteriosis

Answer 15

Aka: vibriosis

• venereal disease of cattle
• early embryonic death, infertility, a protracted calving season, occasionally abortion

Question 16

C. fetus fetus

Answer 16

Cause of vibriosis

- transmitted venereally and by contaminated instruments, bedding, or AI using contaminated semen

Question 17

An infected bull becomes ______

Answer 17

An asymptomatic carrier

Question 18

Vibriosis clinical signs

Answer 18

• endometritis
• early embryonic death
• poor conception rate
• protracted calving periods

Question 19

Vaccination

Answer 19

Should start as soon as genital campylobacteriosis is diagnosed