What are the main issues with case-control studies?
Selection bias, information bias, confounding, Ineffective for rare diseases and it’s difficult to be sure exposure precedes the disease
How do you conduct a case-control study?
Recruit a group of cases, recruit a group of controls, exposure status is then determined
What are case-control studies used for?
Rare exposures, preliminary investigations (cheap & quick)
How can confounders be removed from case-control studies?
Matching up similar cases & controls