cell membranes Flashcards

(36 cards)

1
Q

role of membranes at the surface of the cell

A

-substances leave and enter via the cell
-partially permeable
-substances move via diffusion, active transport and osmosis
-allow cell signalling

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2
Q

role of membranes within cells

A

-compartmentalisation
-provide attachment site for enzymes
-site of chemical reactions

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3
Q

fluid mosaic structure

A

-describes the arrangement of molecules in the membrane
-contains a bilayer
-“fluid” because its constantly moving
-cholesterol is present
-protein molecules are scattered like tiles in a mosaic
-proteins have polysaccharide chains ->glycoprotein
-lipids have polysaccharide chains ->glycolipids

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4
Q

role of the mosaic components for phospholipid

A

phospholipid:
-hydrophobic tail and hydrophilic head
-arrange themselves in a bilayer
-centre is hydrophobic so doesn’t allow water substances-acts as a barrier
-fat soluble substances can dissolve in the bilayer
cholesterol:
-lipid
-fit between phospholipids
low temp.->prevents phospholipids from packing to closely together (increases fluidity)
high temp.->causes them to pack too closely together, makes the membrane less fluid

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5
Q

role of the cholesterol for mosaic components

A

cholesterol:
-lipid
-fit between phospholipids
low temp.->prevents phospholipids from packing to closely together (increases fluidity)
high temp.->causes them to pack too closely together, makes the membrane less fluid

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6
Q

role of the mosaic components for proteins

A

channel proteins-allow small or charged particles through
carrier proteins-transport big molecules and ions across the membrane via active transport and facilitated diffusion

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7
Q

role of the mosaic components for glycolipids and glycoproteins

A

-stabilise the membrane by forming H bonds with surrounding water molecules
-site where drugs, hormones and antibodies bind
-act as receptors for cell signalling
-antigens

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8
Q

how temperature affects membrane permeability

A

below 0C:
-pack closely together and rigid
-channel and carrier proteins deform, increasing the permeability.
-ice crystals pierce the membrane making it highly permeable when it thaws
between 0C-45C
-phospho. can move around
-membrane is partially permeable
-as temp. increases, the permeability increases too
above 45C
-phospho. start to melt and become more permeable, water in cell expands
-channel and carrier proteins deform-increases the permeability of the membrane

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9
Q

how solvents affect the membrane permeability

A

solvents e.g ethanol increase the permeability
-solvents dissolve the lipids so they lose their structure
-some solvents increases cell permeability more than others e.g ethanol increases more than methanol
-increasing the conc. of the solvent increases the permeability

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10
Q

practical for factors affecting membrane structure

A
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11
Q

diffusion as a passive method of movement

A

-net movement of particles from an area of high conc to a lower conc.
-molecules diffuse both ways, but net movement is to a lower conc.
-no energy is needed
-particles diffuse down a concentration gradient

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12
Q

factors affecting diffusion rates in modal cells-practical

A
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12
Q

factors that affect the rate of diffusion

A

-the concentration gradient
-thickness of exchange surface
-the surface area
-temperature

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13
Q

facilitated diffusion

A

-when molecules move particles down a concentration gradient via carrier and channel proteins (for large molecules, ions and polar molecules) in a cell membrane
-passive process

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14
Q

active transport

A

-uses energy to move molecules and ions across plasma membranes against a conc. gradient, involves a carrier protein
-molecule attaches to carrier protein ,protein changes shape and moves across the membrane, releasing it on the other side
-ATP is used to move the solute against the conc gradient

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15
Q

endocytosis

A

-molecules can be too large to be taken into cells via a carrier protein
-A cell can surround a substance with a section of its plasma membrane
-membrane pinches off to form a vesicle containing ingested substances inside
-uses ATP for energy

16
Q

exocytosis

A

Exocytosis is the process by which materials are removed from, or transported out of, cells
The substances to be released (such as enzymes, hormones, or cell wall building materials) are packaged into secretory vesicles formed from the Golgi body
These vesicles then travel to the cell surface membrane
Here, they fuse with the cell membrane and release their contents outside of the cell

17
Q

movement of water across membranes by osmosis

A

-diffusion of water molecules across a partially permeable membrane down a water potential gradient
-water move from an area of higher water potential to a lower water potential
-water potential is the potential of water molecules to diffuse in and out of a solution
-pure water has the highest water potential of 0

18
Q

effect solutions of water have on animal cells

A

hypotonic solution - solution has a higher water potential than the cell (net movement of water is into the cell, cell bursts)
hypertonic solution - solution has a lower water potential than the cell (net movement of water is out of the cell, cell shrinks)
isotonic solution-solution has the same water potential was the cell (water pass into and out of the cell in equal amounts, cell stays the same)

19
Q

effect solutions of water have on plant cells

A

hypotonic solution-net movement is into the cell, vacuole swells cell becomes turgid
hypertonic solution- net movement is out of the cell, cell becomes flaccid cell is plasmolysed
isotonic solution-water molecule ,moves into and out of the cell in equal amounts, cell stays the same

20
Q

explain how anomalous result affects the precision of data obtained

A
  • reduces repeatability of data
  • increases the standard deviation
21
Q

What are the 2 types of endocytosis

A

pinocytosis and phagocytosis

22
Q

whats phagocytosis

A

This is the intake of pathogen by a cell ( phagocyte)

23
Q

whats pinocytosis

A

This is the bulk intake of liquids

24
Glucose can be moved into cells by facilitated diffusion using proteins called GLUT proteins. These proteins expose a single binding site on one side of the membrane. Glucose binds to this site and causes a change in the shape of the protein. This change moves the glucose across the membrane and releases it on the other side. i. Explain why facilitated diffusion via GLUT proteins requires no metabolic energy.
particles have their own kinetic energy movement down concentration gradient
25
Explain why glucose cannot pass through a cell membrane by simple diffusion.
phospholipids act as a barrier (glucose) molecules too large
26
The rough endoplasmic reticulum is where translation of some proteins takes place in a eukaryotic cell. Explain the role of the membrane in the rough endoplasmic reticulum.
* holds ribosomes in place * compartmentalisation
27
Suggest why galactose and glucose cannot pass through the plasma membrane into intestinal cells by simple diffusion through the phospholipid bi-layer.
too large
28
The students concluded that the red pigment began to leak out of the beetroot cells at any pH below pH6.Suggest and explain why a low pH might cause the red pigment to leak out of the beetroot cells.
denatures tertiary structure of proteins therefore membrane permeability is increased
29
Outline how the students could modify their investigation to get a more accurate value for the pH at which the red pigment begins to leak out of the beetroot cells.
use pH buffer range with narrower intervals pH , close to pH6
30
One molecule that crosses membranes easily is the steroid hormone progesterone which is produced in the ovaries from cholesterol. i. Explain why progesterone can move across membranes.
* progesterone is hydrophobic
31
Potassium ions are unable to move across membranes as they are charged. i. State how the structure of the cell surface membrane allows potassium ions to enter or leave a cell.
* channel cotransporter proteins
32
The fluid mosaic model describes plasma membranes of all living organisms. How does the fluid mosaic model describe the structure of plasma membranes?
* phospholipid bilayer * proteins are free to move
33
Cells are surrounded by a plasma membrane that contains phospholipids. Explain how the structure of phospholipid molecules allows for the formation of plasma membranes.
* phosphate is hydrophilic * 2 fatty acid tails are hydrophobic * head orientates towards water and tail orientates away from water
34
Sodium ions and glucose are both reabsorbed into the blood from proximal convoluted tubules (PCTs) in the kidney. i. A student designed an experiment to investigate the effect of temperature on the rate of glucose diffusion through dialysis tubing. State two factors that would need to be controlled in this experiment
* brand of dialysis tubing * glucose concentration
35
Salts that a plant needs, such as nitrates and phosphates, are taken into root hair cells by active transport. For which macromolecule does a plant need both nitrogen and phosphorus?
DNA