why do larger multi-cellular organisms need specialisation? (2 examples of funtions)
what is cell differentiation?
process during development whereby cells become more specialised and distinct as they mature
how does cell differentiation happen?
different genes expressed in different cell types
what affects what cell type it will differentiate into?
location of stem cell in the early embryo, indicates by gradients of signalling chemicals
in the adult body where are stem cells located?
in stem cell niches - environment where they can remain undifferentiated for long time then proliferate when needed
examples of niches (muscle)
striated skeletal muscle stem cells inactive until muscle is damaged - then proliferate and repair
examples of niches (hair)
hair follicles contain stem cells - allow hair growth
totipotent meaing
pluripotent meaning
multipotent meaning
unipotent meaning
example of multipotent cell
Hematopoietic stem cell - found in adult bone marrow, can develop into many types of blood cells
Why is SFA:V ratio important in the limitation of cell size?
Determines the rate at which an organism can take in nutrients from its surroundings
what happens to the SFA:V ratio as the cube gets bigger?
decreases
rbc adaptations to increase their sfa:v ratio
Where is proximal convoluted tubule?
In nephron in kidney
Proximal convoluted tubule adaptations to increase their sfa:v ratio - basal membrane
invaginations - outer basal membrane - close to capillaries
Proximal convoluted tubule adaptations to increase their sfa:v ratio - apical membrane
microvilli - inner apical membrane - in contact w/ the filtrate
what is the alveolar epithelium an example?
Example of tissue with more than one cell type to tend to different functions
what kind of process is the diffusion of CO2 and O2 of Type 1 pneumocytes?
passive price
adaptations of type 1 pneumocytes?
Very wide but very thin cells, reduces diffusion distance
adaptations of type 2 pneumocytes
many secretory vesicles (lamellar bodies)
adaptations to how the alveolus diffuses oxygen
alveolus lined with a film of moisture
Why do muscles work in pairs?