Which substances cannot easily diffuse through the hydrophobic phospholipid bilayer’s core?
Hydrophilic substances
What do larger hydrophilic substances diffuse via?
Protein molecules
Which proteins are involved in facilitated diffusion?
Intrinsic- Channel proteins and carrier proteins
Describe how a carrier protein can move a hydrophilic molecule across a membrane.
-The specific chemical being transported, binds to the carrier protein’s binding site.
-This binding, then causes the tertiary structure of the protein molecule to change.
-This change in structure, brings the chemical, across the membrane and the chemical is then released.
What is the changing of tertiary structure of a carrier protein, also known as?
Allostery
What do protein channels have in their centres?
A channel lined with hydrophilic amino acids and water.
What does the protein channel’s structure allow to pass through the plasma membrane?
Hydrophilic substances.
Are protein channels selective to the chemical they allow to pass through?
Yes
Is each protein channel specific to a certain chemical?
Yes
Describe what is meant by a Ligand-gated protein (/ion) channel?
A protein channel that only opens in response to a specific trigger such as a chemical binding to the protein.
Give an example of a Ligand?
Neurotransmitters
Is facilitated diffusion passive or active?
Passive