Cell surface markers

Question 1

T-cells

Answer 1

TCR
CD3 (assoc. w/ TCR for signal transduction)
CD28 (binds B7 on APC)
CD45RA (naive) —- CD45RO (memory)

Question 2

Helper T-cell

Answer 2

CD4

CD40L

Question 3

Cytotoxic T-cell

Answer 3

CD8

Question 4

Regulatory T-cell

Answer 4

CD4
CD5
CD25
FOXP3

Question 5

B cells

Answer 5

Ig
CD19, CD20, CD21 (receptor for EBV), CD40
MHC II, B7

Question 6

Macrophages

Answer 6

CD14 (co-receptor w/ TLR4) - endotoxin receptor [t-cells not required]
CD40
MHCII, B7
Fc and C3b receptors

Question 7

NK cells

Answer 7

CD16 (binds Fc of IgG)

CD56 (unique marker)

Question 8

Hematopoietic stem cells

Answer 8

CD34