What is cellular respiration?
The process by which glucose is broken down to produce ATP
It involves three stages: Glycolysis, Citric acid cycle, and Electron transport chain.
What does ATP stand for?
Adenosine triphosphate
ATP is used to transfer energy to synthetic pathways and other cellular processes.
What is the role of phosphorylation in cellular respiration?
An enzyme-controlled process that adds a phosphate group to a molecule
For example, phosphorylation occurs when Pi combines with low-energy ADP to form high-energy ATP.
List the three stages of cellular respiration.
Glycolysis occurs in the cytoplasm, the citric acid cycle in the mitochondria, and the electron transport chain on the inner membrane of the mitochondria.
Where does glycolysis take place?
In the cytoplasm
Glycolysis is the breakdown of glucose to pyruvate.
What is the net gain of ATP during glycolysis?
More ATP is generated than used up
This occurs through an energy investment stage followed by an energy pay-off stage.
What is the initial substrate broken down in glycolysis?
Glucose
Glucose is converted to pyruvate during this process.
What are the products of the citric acid cycle?
Hydrogen ions and electrons
These are removed from substrates by dehydrogenase enzymes, releasing ATP.
What is the function of the electron transport chain?
To produce ATP through the transfer of electrons
It takes place on the inner membrane of the mitochondria.
What is the process called that involves the breakdown of glucose to produce energy?
cellular respiration
Cellular respiration includes glycolysis, the citric acid cycle, and the electron transport chain.
During glycolysis, what are the two phases called?
Glycolysis occurs in the cytoplasm and results in the production of ATP and pyruvate.
What is produced when pyruvate undergoes fermentation in the absence of oxygen?
lactate
This process is known as lactate fermentation and occurs in animal cells.
What is the first product formed when pyruvate combines with coenzyme A?
acetyl coenzyme A
This reaction occurs in the matrix of the mitochondria during the citric acid cycle.
What is the cycle that follows the formation of acetyl coenzyme A called?
citric acid cycle
The citric acid cycle generates ATP, releases carbon dioxide, and regenerates oxaloacetate.
What are the two main products generated during the citric acid cycle?
The cycle also regenerates oxaloacetate for continued operation.
What role do dehydrogenase enzymes play in cellular respiration?
They remove hydrogen ions and electrons
These are passed to the coenzyme NAD, forming NADH.
How many ATP are produced during the citric acid cycle?
2 ATP
This production occurs alongside the release of carbon dioxide.
What is the function of coenzyme A in cellular respiration?
It acts as a carrier molecule
Coenzyme A can be recycled and used multiple times in the metabolic processes.
What is the initial substrate for glycolysis?
glucose
Glycolysis begins with glucose and results in the formation of pyruvate.
Where does the electron transport chain take place?
On the folded inner membrane of the mitochondrion
This stage is crucial for ATP synthesis.
What is the role of NADH in the electron transport chain?
Source of electrons
NADH donates electrons to the electron transport chain.
What is produced as a result of the electron transport chain?
ATP
Most ATP is produced by the electron transport chain.
What combines with hydrogen ions and electrons to form water?
Oxygen
Oxygen acts as the final acceptor of hydrogen ions and electrons.
What is the function of ATP synthase in the electron transport chain?
Catalyzes the synthesis of ATP
The rotation of ATP synthase is driven by the flow of hydrogen ions.