Angiogenesis
The growth of new blood vessels from pre-existing vessels.
Science of blood vessels
Angiology = “angio” vessels
Sequence of B.V.
Arteries –> arterioles –> capillaries –> Venules –> Veins
Layers of B.V.
All B.V. have 3 layers except capillaries.
1) Tunica intima
2) Tunica media
3) Tunica externa
Capillaries have:
Types of arteries
1) Elastic 2) Muscular
Elastic Arteries
1) Are closest to the heart. High in elastin
2) Expand during systole acting as pressure reservoir. Very stretchy
3) Recoil during diastole to keep the blood moving
Vascular anastomoses
Muscular Arteries
1) Carry blood to specific organs
2) Tunica media is thick (more smooth muscle)
3) Less stretchy than elastic arteries and more active in vasoconstriction and vasodilation.
Artherosclerosis
degenerative vascular disease that decreases the elasticity of arteries.
1) endothelium is injured
2) lipids accumulate and oxidize
3) smooth muscles cells proliferate and a fibrous cap forms (fibrous lesions with core of dead cells = plaque)
4) plaque enlarges and Ca2+ deposites –> rupture.
Types of capillaries
1) continuous capillaries
2) Fenestrated capillaries
3) Sinusoid capillaries

continuous capillary

fenestrated capillary

Sinusoidal capillaries (sinusoids)

Types of blood circulation(5)
Systemic circulation
Pulmonary Circulation
Coronary circulation
Hepatic circulation
Aorta –> celiac artery (splenic, hepatic, left gastric) –> Hepatic artery –> LIVER <– Hepatic portal veins
LIVER –> inferior vena cava
Hepatic portal veins:

Fetal circulation
what do the anastomoses do?
Provide alternate pathways
anastomoein “supply with a mouth or opening” from stoma “mouth”
vascular anastomoses
Arterial anastomoses
Venous anastomoses
Anastomoses
communication between blood vessels by means of collateral channels, especially when usual routes are obstructed.