Somatic Nervous System
Autonomic Nervous System
Sympathetic and Parasympathetic divisions
-autonomic neurons release mainly ACh and norepinephrine and may be excitatory or inhibitory (ex. raise or lower HR)
Autonomic Neurons
Preganglionic neurons
originate in the midbrain or hindbrain or from the thoracic, lumbar, or sacral spinal cord
Postganglionic neurons
originate in ganglion
Sympathetic Division
preganglionic neurons come from thoracic and lumbar regions (thoracolumbar)
-preganglionic neurons synapse in sympathetic ganglia that run parallel to spinal cord (paravertebral ganglia) –> connected forming sympathetic chain of ganglia
Adrenal Glands
Parasympathetic Division
preganglionic neurons come from the brain or sacral region of the spinal cord (craniosacral division)
Occulomotor Nerve
Vagus Nerve
- preganglionic fibers exit medulla, branch into several plexi and nerves, and travel to ganglia within effector organs
Sympathetic Functions
Parasympathetic Functions
antagonistic to sympathetic
Cholinergic
ACh is used by all preganglionic neurons (sym, para)
Adrenergic
-norepinephrine is neurotransmitter released by most postganglionic neurons
Vericosities
swellings on axons of postganglionic neurons that release neurotransmitter along length of axon
-sympathetic/ parasympathetic neurons innervate the same tissues, but release different neurotransmitter
Adrenergic Stimulation
Adrenergic Stimulation examples
heart, dilatory muscles of the iris, smooth muscles of many blood vessels
Adrenergic Inhibition examples
bronchioles in lungs, other blood vessels
–> inhibits contraction and causes dilation of these structures (ex. skeletal muscles)
Alpha Adrenergic Receptors
A1 and A2 (sympathetic)
Beta Adrenergic Receptors
B1 and B2 (sympathetic)
Cholinergic Stimulation
Cholinergic Receptors: Nicotinic
found in autonomic ganglia
Cholinergic Receptors: Muscarinic
found in visceral organs
Organs with Dual Intervention