What is the order of structures food passes through in the digestive tract?
Mouth → pharynx → esophagus → stomach → small intestine → large intestine → rectum → anus
Explanation: These organs form the GI tract, which breaks food down and absorbs nutrients.
What is peristalsis?
Wave-like muscular contractions that move food forward through the digestive tract.
Explanation: It occurs in the esophagus, stomach, small intestine, and large intestine.
Where does carbohydrate digestion begin?
In the mouth, by salivary amylase.
Explanation: This enzyme starts breaking starch into sugars.
Where does protein digestion begin?
In the stomach, using pepsin and acid.
Explanation: Acid denatures proteins; pepsin cuts them into peptides.
Where does lipid (fat) digestion begin?
Small intestine, with bile + pancreatic lipase.
Explanation: Lipids require emulsification before breakdown.
What are 3 functions of the stomach?
Does the esophagus aid in digestion?
No.
Explanation: It only uses peristalsis to move food to the stomach.
Where does most digestion and absorption occur?
Small intestine.
Explanation: Villi and microvilli massively increase nutrient absorption.
What structures increase surface area in the small intestine?
Villi + microvilli (“brush border”).
Explanation: More surface area = more absorption.
What are the two main digestive functions of the pancreas?
What is a NON-digestive function of the pancreas?
Makes insulin and glucagon to regulate blood sugar.
What does the liver do in digestion?
Makes bile to help digest fats.
Explanation: It also detoxifies blood and stores nutrients.
What does the gallbladder do?
Stores and releases bile.
How does the absorption of lipids differ from proteins?
• Proteins/carbs → blood
• Lipids → lymphatic system first
Explanation: Fats are packaged into chylomicrons too large to enter blood capillaries initially.
What is emulsification?
Breaking large fat droplets into smaller ones (by bile).
Explanation: This increases surface area for lipase to digest fats.
What happens in the large intestine?
• Water absorption
• Vitamin production by bacteria
• Feces formation
Explanation: The microbiome plays a huge role here.
What is the most common cause of stomach/intestinal ulcers?
Helicobacter pylori (H. pylori) bacteria.
Explanation: Antibiotics are used to treat most ulcers now.
Where is the largest amount of bacteria in the digestive tract?
Large intestine.
Explanation: These bacteria influence immunity, mood, weight, and inflammation.
List a few ways the microbiome affects the body.
• Mental health (serotonin production)
• Immune system function
• Brain development
• Digestion efficiency
• Inflammation levels
• Metabolism and weight
• Allergies and autoimmune risks
What can you do to build a healthy gut microbiome?
• Eat fiber
• Eat fermented foods (kimchi, yogurt)
• Avoid unnecessary antibiotics
• Reduce sugar intake
• Exercise
• Sleep well
• Reduce stress
Explanation: The microbiome responds strongly to daily habits.
A person has trouble digesting fats and their stool looks oily. Which digestive organ is likely malfunctioning?
The gallbladder or liver (not releasing bile).
Explanation: Without bile, fats cannot be emulsified.
A patient’s blood sugar stays dangerously high after meals. Which organ may not be functioning properly?
The pancreas (not making insulin).
A person can digest carbs and proteins normally but has trouble absorbing fats. Where is the malfunction?
Lymphatic system or bile production.
Explanation: Lipids must enter lymph first.
A person takes an antibiotic and then experiences digestive issues and depression-like symptoms. Why?
Antibiotics disrupted their gut microbiome, affecting digestion and neurotransmitter regulation.