most commonly affected area of orofacial herpes simplex
outer one-third of the lower lip
rugby
herpes rugbiorum or scrum pox
antimicrobial peptides that inhibit HSV replication
Cathelicidin and beta-defensins
Giemsa or Wright stain (the Papanicolaou staining method also can be used)
multinucleated giant cells that are diagnostic of herpetic infection
Primary infection
Acyclovir, 200 mg orally 5 times a day
Acyclovir 400mg TID
Valacyclovir 1g BI
Famciclovir 250 TID
Reduction of transmission
Valacyclovir, 500 mg orally once a day
Neonatal herpes
IV acyclovir 20mg/kg every 8h x 14-21 days