Chapter 185 :: Retinoids

Question 1

synthetic retinoids

Answer 1

Etretinate

Acitretin

Adapalene

Tazarotene

Bexarotene

Question 2

1-month posttherapy period of contraception provides an adequate safety margin

Answer 2

Isotretinoin

Question 3

2 years compulsory contraception

Answer 3

Acitretin

Question 4

optimal benefit in acne

Answer 4

0.5 to 1 mg/kg of body weight per day

cumulative dose of at least 120 mg/kg

6 to 8 months of therapy

Question 5

central hypothyroidism seen with systemic bexarotene is not observed when used in the gel formulation

Question 6

In men, retinoid therapy does not appear to produce abnormalities in spermatogenesis, sperm morphology, or sperm motility. 69 However, it is usually recommended that men who are actively trying to father children avoid systemic retinoid therapy