Integumentary system
Integumentary system functions
Epidermis
Superficial region
1. Epithelial tissue
2. Avascular
Dermis
underlies epidermis
1. Mostly fibrous connective tissue
2. Vascular
Hypodermis
Insulates and cushions
1. Subcutaneous layer deep to skin
2. Mostly adipose or areolar tissue
3. Anchors skin to underlying structures (muscles)
Thins as we age
Keratinocytes
Dead cells in the epidermis
Stratum granulosum
Stratum lucidum
Stratum basale
Stratum spinosum
Keratinization
Keratinocytes undergo keratinization as they move towards the surface
1. Dead cells
2. Keratin is water repellant
Stratum corneum
Melanin
Pigment produced by melanocytes; stimulated to produce more by sun exposure
Vitamin D
Needed for calcium absorption
Epidermal growth factor (EGF)
Helps the epidermis repair and heal; promotes:
1. Basal cell division
2. Production of keratin
3. Stimulates glands
4. Stimulates growth and repair
Two layers of the dermis
Papillary layer
Reticular layer
Damage to the dermis
Wrinkles (aging)
Cutaneous sensory receptors
Accessory structures
Sebaceous glands
Sudoriferous glands
Hair