Chapter 7: 1.2 - Glomerular Morphologic Changes

Question 1

Glomerular morphologic change:
- results from local chemotactic response or cellular proliferation. -Neutrophils and macrophages can readily infilitrate glomeruli

Answer 1

Leukocyte-membrane infiltration

Question 2

Glomerular morphologic change:

• causes increased numbers of epithelial, mesangial and endothelial cells.
• compose the capillary endothelium and accumulate in the glomerular tuft.

Answer 2

Cellular proliferation

Question 3

Glomerular morphologic change:

results from deposition of precipitated proteins (e.g., immune complexes, fibrin)

Answer 3

Glomerular basement-membrane thickening

Question 4

Glomerular morphologic change:
-results from accumulation of a homogenous, eosinophilic extracellular material in the glomeruli, which causes them to lose their structural detail and become sclerotic

Answer 4

Hyalinization of glomeruli

Question 5

Value for massiev proteinuria

Answer 5

3.5 mg/dl