Pharm 233 > Chemo facts > Flashcards

Chemo facts Flashcards

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1
Q

Proto oncogenes

A

usually control cell division, apoptosis and differentiation
when these are mutated and activated they cause cancer

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2
Q

Tumour suppressor genes

A

usually suppress malignant cells, when these are mutated and inhibited they cause cancer

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3
Q

alkylating agents

A

bind DNA and inhibit replication

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4
Q

Alkylating agents side effects

A

Growth inhibition (no healing, hair growth, bone marrow, height, sperm production)

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5
Q

Antimetabolite side effects

A

bone marrow toxicity
GI tract damage

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6
Q

Topoisomerase inhibitor side effects

A

cardio toxicity
alopecia

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7
Q
A
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