Cholinomimetics

Question 1

Name 2 drugs that can be used in the treatment of Sjögren’s Sydrome.

Answer 1

Pilocarpine (tertiary amine)

Cevimeline (synthetic drug)

Question 2

Besides treating MG , cholinesterase inhibitors can also …

Answer 2

reverse nondepolarizing Neuromuscular blockade
(Neuromuscular blocking agents are used during anesthesia to produce muscle paralysis
: nondepolarizing drugs inhibit nicotine ACh receptors at NMJ)

Question 3

Name the direct acting Cholinomimetics.

Answer 3

M - Bethanechol, Pilocarpine, Methacholine, Muscarine

N- Nicotine, Varenicline, Succinylcholine

M&N- carbachol